In order to resolve the problem met in the pre-treatment of traditional methods for Optical stimulated luminescence (OSL) dating sample which can not obtain enough purity and quantity of quartz, a new quartz separation process in obtained, with contrast experiments, combined with the well-developed quartz purification techniques in glass production, finally a new quartz separation process is obtained. Compared with the traditional methods, the new method adopted by chemical separation to avoid the impact of density of feldspar thus resolves the problem of plagioclase feldspar and debris that can not be removed totally during the traditional methods. The new method can obtain more sufficient purity quartz and at the same time is more efficient in laboratory work.