Regulation indicators for sub-rainstorm quantities currently exhibit deficiencies in various aspects, such as connotation definition, temporal variability, spatial heterogeneity, and multi-objectiveness. These shortcomings have led to a subjective and retrospective evaluation delay in the construction of sponge facilities, thereby hindering the scientific, efficient, and rapid advancement of systematic, full-scale sponge city construction in China. Using the Zhupaichong Basin in Nanning City as an example, a sub rainstorm runoff simulation under multi-objective scenarios of the current underlying surface (2020) was conducted to address the aforementioned regulatory indicator issues. The spatial heterogeneity of the sub rainstorm total control rate and the corresponding comprehensive storage capacity of sponge facilities in this area were analyzed. The results indicated that the average sub-rainstorm total control rate in the study area ranges from 0.500 (0.25 years) to 0.257 (100 years), which is significantly below the 75% control rate target set for the construction of sponge cities in Nanning. To achieve this target, additional comprehensive storage capacities of sponge facilities (excluding external discharge) ranging from 200 m3/hm² (0.25 years) to 950 m3/hm² (100 years) and (including external discharge) from 70 m3/hm² (0.25 years) to 420 m3/hm² (100 years) are required. A quantitative guidance system framework for the continuous promotion of full-scale sponge city construction, termed the “Sub-rainstorm Total Control Rate and Storage Capacity Spatio-temporal Information Map,” was proposed. This framework can comprehensively address the various issues of sub rainstorm quantity regulation indicators and quantitatively guide the multistage design, construction, and operational effectiveness of various sponge facilities, thereby providing crucial support for the scientific, efficient, and rapid advancement of systematic full-scale sponge city construction in China.