Permafrost changes under natural sites along the Qinghai-Tibet Railway were investigated based on the ground temperature monitored from the year of 2006 to 2015. Among these sites, mean permafrost table was 3.54 m, with a range of 0.88 to 9.14 m. Among the sites with decreasing permafrost table, mean decreasing amplitude of permafrost table was 0.51 m, with a range of 0.05 to 2.22 m; mean decreasing rate of permafrost table was 0.07 m/a, with a range of 0.01 to 0.25 m/a. Decreasing amplitude and decreasing rate of permafrost table in high temperature regions were 0.47 m and 0.06 m/a greater than those in low temperature regions, respectively. In general, ground temperatures at permafrost table and 15 m depth presented rising tendency. Mean rising amplitude of ground temperature at permafrost table was 0.16 ℃, with a range of 0.01 to 0.60 ℃; mean rising rate of ground temperature at permafrost table was 0.018 ℃/a, with a range of 0.001 to 0.067 ℃/a. Rising amplitude and rising rate of ground temperature at permafrost table in low temperature regions were 0.12 ℃ and 0.014 ℃/a greater than those in high temperature regions, respectively. Mean rising amplitude of ground temperature at 15 m depth was 0.10 ℃, with a range of 0.01 to 0.48 ℃; mean rising rate of ground temperature at 15 m depth was 0.011 ℃/a, with a range of 0.002 to 0.054 ℃/a. Rising amplitude and rising rate of ground temperature at 15 m depth in low temperature regions were 0.11 ℃ and 0.012 ℃/a greater than those in high temperature regions, respectively. Due to the effect of local factors, increasing of permafrost table and decreasing of ground temperature were observed under several sites.