Deep-sea is one of the most important extreme environments on the earth. Numerous and diverse extremophiles thrive in this extreme environment, presenting distinctive physiological structure, metabolic mechanism and symbiosis relations, which provide new methods to study the origin of life and extraterrestrial life. Despite extensive studies on deep-sea extremophiles from the point of view of biology, the impacts of deep-sea hydrothermal activity on the evolution of extremophiles remain largely unknown. On the basis of summarizing features of the deep-sea ziphysicochemical and geological environment, the distribution and formation mechanism of submarine hydrothermal vents were analyzed, respectively. Hydrothermal vents have great effect on the distribution and succession of communities. Our discussion focused on the extreme life forms of microorganisms surviving in the hydrothermal ecosystem and their important significance for the nutrient cycling and ecosystem evolution. However, the research of life processes in extreme environments is still in the primary stage and more work is needed on the in-situ detection technique, molecular biology and interdisciplinary research.