3D laser scanning has been a new technology in measurement of spatial information in recent years. In this paper, this technology was applied tentatively to the efficiency evaluation of the protective system of sand drift control engineering along Qinghai-Tibet Railway. The sand control efficiency of the system was evaluated by accurately measuring the morphology of sand deposition over the typical sand drift control measures, aeolian erosion and deposition profiles of the cross-section and quantities of erosion and deposition using the 3D laser scanning technology. The concave surface of rocky checkerboard sand barriers easily formed along the perpendicularly direction to the railway. Sand accumulation occured more on the sides of rocky checkerboard than its center. The effective distance of sand fences was about 12 H and sand-blocking volume was 14.93 m³ per 1 m width. Therefore, the space of sand fences should remain 9~12 H in the construction of protective systems. The objective of this study is to extend this technology to the measurement of sand disaster threatening other railways, buildings and engineering measures and to the evaluation of the protective efficiency of their control systems, thus eventually providing technical support to the measure selection, structure optimization and rational distribution of the integrative sand drift control system.