：Zijinshan Gold-copper deposit is attributed to the typical high- sulphidation epithermal deposit. Byingthe electron microprobe (EPMA) test and sulfur isotope analysis of pyrite shows that the generally pyrite is sulfur-rich and iron- deficiency type in this area. From shallow to deep, the S / Fe atomic ratio showing increasing trend. It indicated that a metallogenic environment of highly acidic with high oxygen and sulfur fugacity. The Ni-Codiagrams, As-Co-Ni ternary phase diagrams and standard type features of w(Se) and w(S)/ w(Se) indicated that the pyrite is hydrothermal related to volcanism. Pyrite of this area is the contained gold mineral, the occurrence of gold in pyrite exist in nanoscale particle form. w(Cu + Pb + Zn) of pyrite Tend to gradually increased from shallow to deep. The trace elements lga-lgb of pyrite was positive correlation. The comprehensive trace element ratios Ф of pyrite was gradually decreased from shallow to deep. The sulfur isotope analysis results of pyrite showed that the {Invalid MML} value from -3.0‰ to 3.5‰, with amean of 6.50‰ and average of -0.18‰, which are similar to the magmatic sulfur. According to the typomorphic characteristics of the chemical composition, summarizing the environment of the deposit, the causes information, such as the hydrothermal, the mineral sources and so on .It also provides certain research bases to study the typomorphic characteristic of pyrite composition in the high sulphidation type epithermal gold-copper deposit.