The Weekly successive measurements of ²¹⁰Pb and ⁷Be concentrations in surface air and depositional fluxes at Mt. Guanfeng/Guiyang since December of 2001 indicate that high ²¹⁰Pb concentration is constrained by regional rainfall and air temperature, and shows U-pattern distribution; Seasonal variation of ⁷Be monthly mean concentration is influenced by amount of precipitation and downward stratospheric current; Ratio of ²¹⁰Pb and ⁷Be monthly mean concentrations is determined by ²¹⁰Pb variation and down flow of rich-⁷Be air mass. Ratio of ⁷Be concentration at Mt. Guanfeng/Guiyang and Mt. Waliguan fluctuates rapidly because of their latitudes and elevation, indicating an obvious influence of oceanic poor-⁷Be air mass invasion on Mt. Guanfeng. Annual mean concentration of ²¹⁰Pb at Mt. Guanfeng/Guiyang during 2002-2008 is about 2.8 ± 0.6 mBq/m³, nearly 4 times of the average concentration of the highest concentrations of the global observations; 4.8 ± 0.6 mBq/m³ for ⁷Be, which is equivalent to the average concentration of the highest concentrations of the global observations and 1/3.8 times of the ⁷Be activity (18.0 mBq/m³) on the top of the troposphere at middle latitude of northern hemisphere; it is anticipated in the low latitude and high elevation area. In 2003, the ratio of annual mean 7Be concentration is 3.8 at both Mt. Waliguan and Mt. Guanfeng, which is consistent with the anticipated consequence of atmospheric transportation and mixture. Increasing trend of ⁷Be monthly mean concentration relates to decrease of sunspot number, the baseline of the influence for ⁷Be is about 4 mBq/m³; Increasing trend of ⁷Be annual mean concentration could also be influenced by sunspot number decrease. Volume-weighted concentrations of 7Be and 210Pb in rainfall at Mt. Guanfeng/Guiyang are 0.72 Bq/L and 0.27Bq/L, respectively; their annual depositional fluxes are 0.080 Bq/( cm²·a) and 0.031 Bq/( cm²·a), respectively. The numerical simulation shows global zonal distribution of ²¹⁰Pb with mosaic areas of high air concentration and high fluxes, which confirms the simulated results of ²¹⁰Pb and ⁷Be inventories in the sediments of Lake Hongfeng and Erhai.