The weathering and riverine loads play an important role in studying the sea-land matter balance and global climatic change. The dissolved and particulate loads of the river are used to estimate the physical erosion and chemical weathering rates over the world drainage basins, respectively. The effect of the rock types, relief, runoff, climate, vegetation and human activity on weathering are summarized in detail at a global scale. The rock types are responsible for the dissolved and particulate loads of the major world rivers .The correlation between the relief and runoff and particulate loads is stronger than the correlation between the climate and particulate loads, while the climate and runoff have a critical
influence on chemical weathering and solute fluxes. More attentions are paid on the effect of vegetation and human activity on the dissolved and particulate loads. A preliminary linkage of the model CO2 consumption by chemical weathering and the global climatic change is also examined based on the literature review.