Two main types of pollution sources of surface waters can be generally characterized as point and nonpoint (i.e. diffuse) sources.While point sources are for the most part relatively well characterized and controlled, nonpoint sources become more and more important and are being increasingly recognized as significant aquatic pollution sources. This paper reviewed the research status of the hydrological models and nonpoint pollution models, analysed some famous and commonly-used models such as CREAMS, GLEAMS, HSPF, ANSWERS, AGNPS, etc., then discussed the significance, levels and methods of integrating RS, GIS and nonpoint pollution models. The authors also elucidated 3 levels of the integration: ①The basic level—establishing the database for the nonpoint sources based on GIS;②The second level—integrating the RS and GIS with nonpoint pollution models, such as parameter estimation, visualization for simulation results using GIS; ③The third level—establishing the comprehensive and integrated simulation system based on RS and GIS. Finally four aspects of the prospects and trends of nonpoint pollution models are analysed:①Establishing the integrated simulation system which can describe interactions between atmospheric, hydrological processes and water quality responses.②Establishing the nonpoint pollution model system based on GIScience.③Focusing on the research of nonpoint pollution simulation in the plain catchment area.④Focusingon the toxic pollutants such as VOCs, PAH, PCBs,etc., in the nonpoint pollution simulation.