Abstract：The North China region is one of the important grain production bases in China, while climatic drought is the main natural disaster affecting agricultural production, always resulting in immense lose for the agriculture. Hence, exploring the spatiotemporal evolution and formation mechanism of drought in North China is an important basis for a quantitative understanding of drought mechanisms as well as the scientific prevention and control of drought disaster risk, insuring regional and even national food security. based on SPEI-3 and largescale circulation data, this study investigated systematically the spatial variation pattern of drought events during the growth period of winter wheat and its potential influencing factors from the perspective of key growth stages, by combining run length theory, cluster analysis and wavelet transform coherence methods. The results showed that the climate during the growth period of winter wheat in North China from 1961 to 2021 has been becoming moist, especially from the booting stage to the maturity stage, with humidification in Hebei, Henan, and Shandong provinces, and drying tendency in Shanxi province. Henan Province and its surrounding areas were characterized by larger frequency and shorter duration of drought were in during the growth period of winter wheat, while droughts in Hebei Province and northern Shandong Province were characterized by long duration, low frequency and high severity. The spatial clustering patterns of drought event appeared different during individual growth period. SPEI-3 was strongly related to circulation factors during the entire growth period, emergence-tillering period, overwintering-jointing period, and booting-maturity period of winter wheat, with critical influencing factor of TNA, PNA, AO, and NINO34, respectively. The results of this study could provide regional specific valuable insights for agricultural drought resistance and disaster reduction decision-making in North China.