Ice thickness and storage are prerequisites for glaciological studies that predict future glacier changes, estimate available freshwater resources, and assess potential sea level rise. Based on Ground-Penetrating Radar (GPR) thickness data from 31 glaciers in western China, the parameters of the GlabTop2 (Glacier Bed Topography) model were calibrated and optimized. The simulation of ice thickness on the Qiangtang Plateau and the assessment of the total amount of glacier water resources revealed the following results: \mathrm{①} The average ice thickness simulated by the GlabTop2 model closely matched the measured average thickness, with a correlation of 0.87 and root-mean-square error of 18.2 m. Overestimation and underestimation of ice thickness by the model were 9% and -17% respectively. The ice thickness distribution along flow was better captured than the distribution across flow; \mathrm{②} The GlabTop2 model estimated that the ice storage of glaciers on the Qinghai-Xizang Plateau in 2022 was (177.6±26.6) km³, with an average ice thickness of (88.2±12.3) m. The glacier volume was mainly distributed between 5 600 and 6 200 m, amounting to (148.28±22.24) km3, which accounted for 84.4% of the total glacier volume of the Qiangtang Plateau. The glacial volumes in the other elevational bands were relatively small.