Earthworm calcite granules (ECG), generally produced in Morren's glands of the earthworm Lumbricus terrestris and Lumbricus rubellus, are commonly preserved in Quaternary soils and sediments well. These granules can not only provide radio-carbon dating (Carbon-14) with the efficacious materials, but accurately record a wealth of climatic and environmental information on temperature and precipitation. For instance, researchers from France reconstructed the paleotemperature and paleoprecipitation during the last glacial in west part of Europe by taking advantage of δ¹⁸O and δ¹³C signal contained in ECG. Additionally, scientists from Germany and France carried out radiocarbon dating of ECG from two different loess-paleosol sequences, and the results showed consistency with the dating results of other materials (such as charcoal, bone, plant calcified root cells, etc.). Therefore, this new bio-indicator has been confirmed as a proxy for paleoenvironmental and paleoclimatic reconstruction, hopefully becoming the golden key to understanding the paleoclimate change. This paper, based on the previous literatures, reviewed the present research status of ECG in paleoclimatology, mainly consisting of five aspects: (i) ECGs' production mechanism and their characteristics; (ii) The theoretical foundation of stable carbon and oxygen isotopes in terrestrial fossil earthworm calcite granules for paleoclimatic reconstruction; (iii) The pre-treatment of ECG samples; (iv) Current applications in chronology and paleoclimatology of earthworm calcite granules;(v) Major problems at present regarding paleoclimatic explanation and radiocarbon-14 dating of ECG. Finally, we proposed the future research and development direction in this field, which is expected to make a reference to the future researches.