The study of the economic impact of climate change has received extensive attention from governments and scholars around the world. This paper based on 14 796 literatures that related to climate change and economic from the core database of Web of Science. Integrating the method of co-citation network and burst keywords co-occurrence network to analyze the temporal and spatial changes of research hotspots on climate change and economic impact. The results show that the global literature's number keep a exponential growth trend, rapidly after 2007. Before 2007, the research hotspots primarily centered on the climate change attribution analysis (increased CO2 emissions from fossil fuels, land use changes, etc.), the impact on natural ecosystems (agricultural production, food security, Arctic ice caps, coastal zones, etc.) and socio-economic System (human health, energy, industry, etc.), and the assessment of economic impac and then focused on the future scenarios of climate change and CO2 abatement and how to adapt and mitigate the climate change. After 2007, with the introduction of IPCC AR4 and Stern report, further strengthened the research on cost-effective assessment of climate change impact, vulnerability, bioenergy and so on. The research hotspots focus on economics of climate change and trade. In space, the literatures of research hotspots were mainly come from the United States, Canada, Western European countries (UK, France, Germany, Italy, Netherlands), Australia and China.