Altered submarine basalts with rich secondary calcites were graded, homogenized, and divided into 49 subsamples. 48 subsamples were leached with hydrochloric acid (HCl) of different concentrations (0.25 mol/L, 0.5 mol/L, 1.0 mol/L, 1.5 mol/L, 2.0 mol/L, 2.5 mol/L) for different time periods (0.5 hour, 1 hour, 2 hours, 4 hours, 16 hours, 32 hours and 64 hours). The main oxides and trace elements in the leached residuals were analyzed to determine the preferred HCl concentration-time combinations for leaching secondary components in altered submarine basalts. The result indicates that there are 9 optimal schemes as preferred HCl concentration-time combinations to leach secondary components in altered submarine basalts, which are 1.0 mol/L-0.5 hours, 1.0 mol/L-1 hour, 1.0 mol/L-2 hours, 1.0 mol/L-4 hours, 1.5 mol/L-0.5 hours, 1.5 mol/L-1 hour, 2.0 mol/L-0.5 hours, 2.0 mol/L-1 hour and 2.5 mol/L-0.5 hour.