Based on regional combination of the hazard-formation factors and hazard-affected bodies, distributing disciplinarian of the agriculture hazard-affected bodies and the centers of drought disaster in China are found. According to the primary style of hazard-affected bodies, such as the rainfed field (Xinghe County), the irrigated field (Xingtai County) & the paddy field (Dingcheng County), this paper sets up vulnerability identification index system of agriculture drought disaster; establishes regional assessment model of agriculture drought vulnerability, such as the frangibility-adaptability model of the rainfed field, the production-living pressure model of the irrigated field and the water demand-supply model of the paddy field. Taking Xinghe County as a case, agriculture drought vulnerability assessment is also carried. The formation of hazard-affected bodies vulnerability and regional sustainable development is discussed, and some scientific advices for the defense of agriculture drought disaster and disaster mitigation are put forward.