Based on electron microprobe analyses of garnets, pyroxenes, amphiboles and plagioclases from mafic deep-derived enclaves in Liuhe-Xiangduo area, eastern Tibet, calculated equilibrium temperatures of the enclaves by Grt-Cpx geothermometers (T_EG79, T_P85,T_K88, and T_R2000), Grt-Hblgeothermometers (T_GP84and T_RV2000), and Hbl-Plgeothermometers (T_BH90), and equilibrium pressures by aluminum-in-amphibole geobarometrys (P_Al-in-Hbl). The results showed that equilibrium temperatureand pressureconditions of garnet diopsidite, garnet amphibolite, garnet hornblendite, amphiboliteand hornblenditewere 770~920 ℃ and 0.83~1.50 GPa (equivalent to27~50 km depth), 730~950 ℃ and 0.85~1.04 GPa (28~34 km), 720~900 ℃ and 0.74~1.32 GPa (24~44 km), 512~753 ℃ and 0.71~0.98 GPa (23~32 km), and 0.60~0.84 GPa (20~28 km). The P-T conditions in the enclaves revealed the former three types of enclaves came from low-crust with higher P-T (720~950 ℃ and 0.74~1.50 GPa), and the latter two derived from middle-crust with lower P-T ( 510~735 ℃ and 0.60~0.98 GPa). The P-Tconditionof enclaves still indicated the source depth of the high-K magma is 50km at least. 