Geographical science system deals with the study of interrelation and interaction between man and nature (environment). Owing to the importance of mankind in the Earth system changes since Holocene, a new sphere-Anthropo-sphere is added to physical spheres on the Earth in geographical science system and designated as the equivalent to the summation of all physical spheres. In the diagram (Fig.2), Anthropo-sphere is placed in the center and its interrelations with physical spheres are shown. This is an innovation point in the global change study. Moreover, the study of geographical science system is connected to the global change study in this way, facilitating Chinese geographical research work open to the world.
The Yangtze River Delta is designed as a region to test the validity of the theory of geographical science system and the guidelines for research are also suggested.
The ultimate aim of the study of geographical science system is to provide scientific basis for the sustainable development of the region. The key issues of the sustainable development of the Yangtze River Delta are highlighted.