GPS radio occultation technique was developed from the application of remote sensing technique in planet atmospheric limbing sounding. based on the seggestion of GPS radio occultation，GPS/MET proposal comeinto a formal experiment stage with the launch of satellite MicroLabl in Arp. 3，1995. The results from the experiment has proved the potential scientific value and practical significance of this technique in earth atmospheric limb sounding. In this paper，it is briefly and systematically introduced on how to apply the technique of GPS radio occultation to measure and monitor the vertical profile of the global atmospheric refractive index，temperature，pressure and moisture.  Preliminarily results from simulations and experiments are also outlined. Some potential contributions of the GPS radio occultation technique to the monitoring of the global climates change and to the improvement of the weather analysis and prediction accuracy.