The behavior of UO₂ corrosion and the fate of radionuclids released during the corrosion of UO₂ are of critical signification for performance assessment of a spent fuel repository. In laboratory, therefore, corrosion of UO₂ and mobility of radionuclids during the corrosion are detailedly researched by many researchers. However, the short-term experiment results may not be extrapolated to the long-term corrosion behaviors of the spent fuel in repository, and natural analogy provides a possibility for this extrapolation. Consequently, many studies on natural analogy were conducted. In this paper, the progresses acquired in the studies of natural analogy are summarized, including a comparison of structural properties, radiation damage and chemical composition between uraninite and UO₂, combination and paragenesis of alteration products of uraninite, chemical composition of uraninite and its secondary phases, mobility of analogy elements in the process of uraninite alteration. In addition, the problems in next studies are pointed out, e.g., characterization of micro-structure of secondary uranium minerals, high-resolution analyses of trance elements distributed in original and secondary uranium minerals using laser microprobe analyzer, composition of underground water, simulation experiments.