Studies of the rapid climate changes through high-resolution deep-sea sequences represent an important legacy of the Ocean Drilling Program (ODP) and related International Marine Global Change Study (IMAGES). It has been revealed that decadal to millennial-scale climate variability is a global phenomenon, which was not limited to the ice cores and high latitudes of the North Atlantic, but also extended to other oceans such as the tropical Pacific and other parts of the globe. These rapid climate changes occurred in the last glacial stage, but also in the Holocene and the middle and early Pleistocene. Despite its reason and mechanism are still vigorously debated, it has been clearly shown that some elements (e.g., tropical forcing, solar activity) different from the glacial-interglacial ice cover volume change were responsible for the rapid climate changes. This fundamentally altered the way Earth scientists thought about the operation of the Earth's climate system and the relatively sensitivity of this system to major climatic shifts.