Multiphase fluid flow, Conductive and convective heat transfer, intrinsic kinetics of hydrate decomposition, and deformation of sediments are four basic physicalchemical processes in the exploitation of gas hydrate. The multiphase fluid flow leads to the pore pressure dissipation and the deformation of hydrate bearing sediments (HBS) accompanied by the convective and conductive heat transfer, and then the hydrate recovery. The absolute permeability of HBS is one of the key controlling factors. The advances in the absolute permeability with the qualitative and experienced relations to pore-scale distribution of hydrate, porosity, saturation of hydrate, and effective stress of HBS are summarized. The main directions and issues on the absolute permeability in the multiphase fluid flow of the HBS exploitation are presented.