The function of human factors in Water-Ecology-Economy System is becoming more outstanding. The practice of water resource management is also crying for more and more researches on human factors' function and its effect in aspects of different space time and analysis dimension. Hence, more countermeasures from broad social-economic vision will be found to resolve the water resource problem. The paper analyses the main trend and focus in Human-Earth System research, reviews the correlative progress at home and abroad and finally puts forward some expectation on the function of human factors in Water-Ecology-Economy System of typical inland river basin in Northwest China.