Globalization is the most influencing event in the 21st century and it will promote global urbanization to develop rapidly. In the period of rapid urbanization, urbanization in China takes on many new characteristics and faces problems, such as “cluster development” of urbanization, duality structure of urban and rural, “driven urbanization” and differences of regional space. The new conflicts, deterioration and impropriation of water and land bring on many negative effects on regional environment in Chinese coastal cities, such as acid rain, urban pollution, automotive fog and traffic jams. In the face of effect and impact of globalization, the anthors pointed out that we should make Chinese urbanization in a healthy way urbanization from the angle of regional space and directed by scientific ideas and building of harmonious society. We should pay much attention to the protection and construction within the urban clusters, adjust measures to local conditions, reasonably develop, structure the regional ecological safe pattern and promote information cooperation.