This paper reviews the 15-year development process of the Integrated Risk Governance Project (IRGP) under IHDP/Future Earth, summarizes its major research achievements, and provides prospects for future research directions in this field. The first five years of IRGP (2010-2014) were carried out under the International Human Dimensions Programme on Global Environmental Change (IHDP), focusing on global integrated risk governance research. Six main research themes were included: social-ecologic system, model and modeling, entry mechanism, early warning system, case comparison, risk governance paradigms. Over the past ten years, IRGP has continued under the framework of the Future Earth (FE), jointly initiated and led by the International Science Council (ISC, formed through the merger of ICSU and ISSC) and United Nations system organizations such as UNESCO, UNEP, and UNU. Its main research directions have included: natural disaster and advanced technology risks, climate change risks in coastal regions, risks from urbanization and agriculture, financial and global systemic risks, as well as green growth and integrated risk management. Major achievements of IRGP include: the paradigm of comprehensive disaster reduction and risk defense—the consilience model, compilation of the Atlas of Natural Disasters in China, compilation of the World Atlas of Natural Disasters, comprehensive rapid assessment studies of global compound chain disasters and mega-disaster risks, construction of the global environmental risk governance paradigm, and systematic analyses of Earth environmental risk prevention and control. Comparing IRGP’s 15-year research progress with the trends of international political, economic, social, environmental, and technological development, future integrated risk governance research should address systemic risks of the Earth and the world, focusing on the trinity of tackling global climate change, reducing disaster risks, and achieving sustainable development. It is advisable to promptly establish an international science programme for integrated disaster risk prevention based on the successful experience and existing work of IRGP, as it is highly essential for ensuring the security and sustainable development of the community with a shared future for mankind.