Delimitation of the continental shelf is an emerging interdisciplinary discipline in the field of international marine science and technology. It uses the scientific and technological means to expand the jurisdiction of coastal states based on the international rules of the 《United Nations Convention on the Law of the Sea》. Therefore, it is related to the marine sovereignty rights and interests of a country and also a hot topic of science and technology that all countries have competed to develop. China has launched the research in this field simultaneously with the world's maritime powers, and formed its innovative advantages in such aspects as geological models, detection techniques and delimitation systems in the delimitation of continental shelf, which have become the brand new ties for China's cooperation with foreign countries in marine science and technology, and also the important field in the maritime silk road cooperation in the 21st century. This paper introduced the basic principles and methods in the delimitation of continental shelf beyond 200 nautical miles (370 km), progress in the delimitation of the global continental shelf, and China's innovative science and technology as well as its application in maritime Silk Road cooperation, and provided the prospect of the future scientific and technological cooperation with foreign countries and development in this filed. And it was suggested China should develop the scientific and technological cooperation on the delimitation of the continental shelf along the Silk Road, promote the scientific and technological development of the delimitation of the continental shelf in China, and enhance China's influence and voice in international ocean affairs.